Journal: BMJ Global Health
Article Title: Investing in a global pooled-funding mechanism for late-stage clinical trials of poverty-related and neglected diseases: an economic evaluation
doi: 10.1136/bmjgh-2023-011842
Figure Lengend Snippet: Conceptual diagram of modelling approach. The overall model consists of three main components: (1) the DES model that projects the number of product launches and the clinical trial costs, (2) the economic and health benefits model which projects the potential economic and health benefits from product launches and (3) the economic analyses that calculate the BCRs and ICERs of the different design options. BCRs benefit–cost ratio; DES, discrete event simulation; ICERs, incremental cost-effectiveness ratio.
Article Snippet: We developed a discrete event simulation (DES) using the MATLAB-based simulation tool SimEvents ( ).
Techniques: